Comorbidities in Prognostication in Cancer
Principal Investigator: Jay Piccirillo MD

• Publications
  • Planned submission to Statistics in Medicine
  • Web applications of prognostic algorithms
• Presentations
  • Planned presentation to insurance industry meeting, April 2004
• Grants
  • Applications for further funding to NIH/NCI (Cancer Communication and Interactive Media Technology) and private foundation support (James S. McDonnell Foundation/Studying Complex Systems)

QOL Feedback to Improve Physician Patient Communication and Patient Outcomes
Principal Investigator: Thomas Burroughs PhD

• Publications
  • "Diabetes Quality of Life - Short Form: A mechanism for assessing patient health status issues in physician office settings" under review in Diabetes Spectrum

Productive Engagement in Older Adults
Principal Investigator: Nancy Morrow-Howell PhD

• Publications
  • Morrow-Howell N. Hinterlong J. Rozario PA. Tang F. Effects of volunteering on the well-being of older adults. Journals of Gerontology Series B-Psychological Sciences & Social Sciences. 58(3):S137-45, 2003.
• Grants
  • With Ford Foundation support, extension and preparation of major proposal.
    

Variations in Breast Cancer Screening
Principal Investigator: Mario Schootman PhD

• Publications
  • Schootman M, Jeffe DB. Identifying factors associated with disability-related differences in breast cancer screening (United States). Cancer Causes Control 2003 Mar;14(2):97-107.
• Grants
  • R21 NCI - GIS and Breast cancer screening in St. Louis ($100k for each of two years)
  • Modeling community disparities in breast cancer screening. Submitted to AHRQ, received high priority score; funding decision due by 10/03.

Peer "Coaches" to Motivate Diabetes Management
Principal Investigator: Kathleen Tarr MD

• Publications
  • Two papers in progress
• Proposals
  • NIH career grant and RWJ Generalist Scholar applications submitted
• Presentations
  • Abstract presented at the 63rd Scientific Sessions of the American Diabetes Association, New Orleans, LA, June 2003.
    

Risk Adjustment in Atrial Fibrillation
Principal Investigator: Brian Gage MD

• Publications
  • Kerzner R, Gage BF, Freedland KE, Rich MW. Predictors of Mortality in Patients with Heart Failure and Preserved Left Ventricular Systolic Function. Am Heart J 2003;146:286-90.
  • Manuscript under development: A comparison of methods of comorbidity adjustment using administrative data.
• Grants
  • Pharmacogenetics, Biomarkers, and Antithrombotic Therapy, R01 HL074724 is pending. Decision due October, 2003
    

Data Mining in Predictors of Suicide
Principal Investigator: Rumi Price MD

• Publications
  • Price RK, Risk NK, Haden AH, Russell KL, Virgo KS, Spitznagal EL. Post-traumatic stress disorder, substance abuse and suicidal behavior among Vietnam veteran males with a history of heavy substance abuse. Accepted for publication in Drug & Alc Dependence 2004
• Presentations
  • Price RK, Risk NK Capturing the "rock-bottom" phenomena in the gradual process of substance abuse remission: Artificial neural networks analyses. Poster presentation at the Sixty Fifth CPDD Annual Scientific Meeting, Bal Harbour, Miami, June 2003.
  • Price, RK. Suicide and suicidal behavior in Vietnam veterans. NIDA/UR Center for the Study and Prevention of Suicide. Drug Abuse and Suicidal Behavior Workshop. Washington, D.C., March, 2003.
  • Price, RK. Trauma, PTSD, substance abuse and suicidal behavior in middle aged men. Grand Round lecture. University of Rochester Center for the Study and Prevention of Suicide, Rochester, NY, October, 2003.
• Grants
  • Genetic Epidemiology of Substance Abuse: Pacific Rim Project - Phase I (R01-DA under review, June 2003). P.I. Price, $4.08 million. St. Louis is the Coordinating and Steering Site for the multi-site coordinated program project involving sites in Tokyo, Japan, Hanoi, Vietnam, Honolulu, Hawaii, East Bay area, California, and St. Louis, Missouri (total of approximately $10 million, involving data collection of over 4,000; DA017814-01, DA017811, DA017818, DA017826
  • Competitive supplement, Follow-Up of Vietnam Veterans at Risk for Suicide (RO1-MH60961), P.I. Price288K (under review, June '03, priority score 165), 2003-2006. [NB. Two of the data mining approaches are proposed here and also use data analysis results from the LLF foundation activities.]
    

Disease Comorbidity and Survival in the NHLBI Family Heart Study (FHS)
Principal Investigator: Michael Province PhD

• Grants
  • 1 U01 HL72524 Province, Michael 9/30/2002 - 9/29/2006
    NIH $247,126.00
    Genetic and Environment Determinants of Triglycerides
    Assess the phenotypic response to treatment according to the genetic variation in the
    candidate genes of interest and perform molecular genetic studies to identify new sequence variation in the ApoA 1 gene and other informative candidate loci that may predict treatment response.
  • 1 R01 HL68891 Myers 12/1/2001 - 11/30/2004
    NIH $83,632.00
    Epidemiological and Genetic Studies of Body Mass Index
    Using NHLBI Family Heart Study data, this study proposes to look at both the genetic and the epidemiological factors that effect body mass index
  • 1 R01 HL67899-01 Province, Michael 9/1/2001 - 8/31/2005
    NIH/NHLBI $238,421.00
    GENCAC - Data Coordinating Center
    The purpose of Genetics of Coronary and Aortic Calcification (GENCAC) is to identify genetic factors that establish susceptability to (a) coronary and aortic atherosclerosis and (b) inter-individual variability in the inflammatory response.
  • 1 R01 HL56567-05A1 Province, Michael 8/15/1996 - 6/30/2004
    NIH/NHLBI $441,480.00
    FHS: Molecular Genetics and Genetic Epidemiology
    Coordinating center to provide data base management and genetic analysis of family data on CVD.