Publications Recognizing Longer Life Foundation Support

2010

Extending healthy life span – From yeast to humans.
Fontana L, Partridge L, Longo, VD.
Science 2010 328, no. 5976:321-326
Pubmed abstract (Pay to view)

Long-term effects of calorie restriction on serum sex-hormones concentration in men.
Cangemi R, Friedmann AJ, Holloszy JD, Fontana L.
Aging Cell 2010 Apr 9(2):236-242.
Pubmed abstract (Pay to view)

Calorie restriction and cancer prevention: metabolic and molecular mechanisms.
Longo VD, Fontana L.
Trends in Pharmacological Sciences 2010 31(2):89-98
Pubmed abstract

Effects of long-term calorie restriction and endurance exercise on glucose tolerance, insulin action, and adipokine production
Fontana L, Klein S, &  Holloszy JO
AGE 2010 32:97–108
Pubmed abstract

TRB3 Function in Caardiac endoplasmic reticulum stress
Avery J, Etzion S, DeBosch BJ, Jin X, Lupu TS, Beitinjaneh B, Grand J, Kovacs A, Sambandam N, Muslin AJ
Circulation Research 2010  106:1516-1523
Pubmed abstract (Pay to view)

A possibility of nutriceuticals as an anti-aging intervention: Activation of sirtuins by promoting mammalian NAD biosynthesis
Imai, S
Pharmacological Research 2010 62:42-47
Pubmed abstract

Organizational Support and Volunteering Benefits for Older Adults
Tang F, PhD*, Choi E, & Morrow-Howell N
The Gerontologist 2010 1-10
Pubmed abstract (Pay to view)

2009

“Clocks” in the NAD World: NAD as a metabolic oscillator for the regulation of metabolism and aging
Imai, S
Biochimica et Biophysica Acta Proteins and Proteomics
http://www.sciencedirect.com/scidirimg/clear.gifAbstract 
Pubmed abstract

Driving retirement in older adults with dementia.
Crouston J, Meuser TM, Berg-weger M, Grant E, Carr DB.
Topics in Geriatric Rehabilitation 2009 25 (2):154-162
Abstract (pay to view)

The scientific basis of caloric restriction leading to longer life.
Fontana L.
Current Opinion in Gastroenterology 2009 25:144-50
Pubmed abstract

Modulating human aging and age-associated diseases.
Fontana L.
Biochimca et Biophysica Acta 2009 1790 (10) 1133-1138
Pubmed abstract

Productive Engagement and Late Life Physical and Mental Health: Findings from a Nationally Representative Panel Study.
Hinterlong JE, Morrow-Howell N, Rozario PA.
Research on Aging 2007; 29; 348
Pubmed abstract

SIRT1 and caloric restriction: an insight into possible trade-offs between robustness and frailty.
Imai S.
Curr Opin Clin Nutr Metab Care 2009 12(4):350-6
Pubmed abstract

Who benefits from volunteering: Variations in perceived benefits.
Morrow-Howell N, Hong SI, Tang F.
The Geriontologist 2009 49 (1):91-102
Pubmed abstract

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis.
Ramsey KM, Yoshino J, Brace CS, Abrassart D, Kobayashi Y, Marcheva B, Hong HK, Chong JL, Buhr ED, Lee C,Takahashi JS, Imai D, Bass J.
Science 2009 324:651-54
Pubmed abstract

2008

MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets.
Muslin AJ
Clin Sci (Lond). 2008 115(7):203-18.
Pubmed abstract

The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan.
Collins JJ, Evason K, Pickett CL, Schneider DL, Kornfeld K.
PLoS Genet. 2008 4(10):e10000230
Pubmed abstract

The measurement and analysis of age-related changes in Caenorhabditis elegans.
Collins JJ, Huang C, Hughes S, and Kornfeld K.
WormBook 2008 Jan 24:1-21
Pubmed abstract

Restriction of overweight and eating disorder symptoms via the internet in adolescents: A randomized controlled trial.
Doyle AC, Goldschmidt MA, Huang C, Winzelberg AJ, Taylor CB, Wilfley DE.
Journal of Adolescent Health 2008 43 (2):172-179
Pubmed abstract

Valproic acid extends Caenorhabditis elegans lifespan.
Evason K, Collins JJ, Huang C, Hughes S, Kornfeld K. 
Aging Cell 2008 7(3):305-347
Pubmed abstract

Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans.
Fontana L, Weiss EP, Villareal DT, Klein S, Holloszy JO. 
Aging Cell 2008 7(5):681-87
Pubmed abstract

Translational approaches to addressing complex genetic pathways in colorectal cancer.
Early DS, Fontana L, Davidson NO.
Translational Research 2008;151:10-16
Pubmed abstract

Calorie restriction and cardiometabolic health.
Fontana L.
European Journal of cardiovascular prevention and rehabilitation. 2008;15(1):3-9.
Pubmed abstract

Changes in weight and health behaviors from freshman through senior year of college.
Racette, SB, Deusinger SS, Strube MJ, Highstein GR, Deusinger RH.
J Nutr Educ Behav 2008;40(1):39-42.
Pubmed abstract

 
2007

Aging, adiposity and calorie restriction.
Fontana L, Klein S.
JAMA 2007 Mar 7;297(9):986-94.
Pubmed abstract
Free full-text: http://jama.ama-assn.org/cgi/reprint/297/9/986

Evaluation of cognitive impairment in older adults: combining brief informant and performance measures.
Galvin JE, Roe, CM, Morris JC.
Arch Neurol 2007 May,64(5):718-24.
Pubmed abstract
Free full text: http://www.alzforum.org/images/livedisc/galvin.pdf

Patient’s rating of cognitive ability: using the AD8, a brief informant interview, as a self-rating tool to detect dementia.
Galvin JE, Roe CM, Coats MA, Morris JC.
Arch Neurol 2007 May;64(5):725-30.
Pubmed abstract
Free full-text: http://www.alzforum.org/images/livedisc/GalvinAD8.pdf

Quantifying the usefulness of CT in evaluating seniors with abdominal pain.
Lewis LM, Klippel AP, Bavolek RA, Ross LM, Scherer TM, Banet GA.
European Journal of Radiology 2007;61(2):290-96
Pubmed abstract
Full text: http://linkinghub.elsevier.com/retrieve/pii/S0720-048X(06)00408-6


2006

Effects of anticonvulsant drugs on lifespan.
Evason K, Kornfeld K.
Arch Neurol 2006 Apr;63(4):491-6.
Pubmed abstract
Free full-text: http://archneur.ama-assn.org/cgi/reprint/63/4/491?ck=nck

Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
Collins JJ, Evason K, Kornfeld K.
Exp Gerontol 2006 Oct;41(10):1032-9.  
Pubmed abstract

Validity and reliability of the AD8 informant interview in dementia.
Galvin JE, Roe CM, Xiong C, Morris JC.
Neurology 2006 Dec 12;67(11):1942-8.
Pubmed abstract

 Effect of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults.
Villareal DT, Miller BV III, Banks M, Fontana L, Sinacore DR, Klein S.
Am J Clin Nutr 2006 Dec;84(6):1317–23.
Pubmed abstract


2005

Anticonvulsant medications extend worm life-span.
Evason K, Huang C, Yamben I, Covey DF, Kornfeld K.
Science 2005 Jan 14;307(5707):258-62.
Pubmed abstract
Free text (with registration): http://www.sciencemag.org/cgi/content/full/307/5707/258

The AD8: a brief informant interview to detect dementia.
Galvin JE, Roe CM, Powlishta KK, Coats MA, Muich SJ, Grant E, Miller JP.
Neurology 2005;65(4):559-564
Pubmed abstract
Full text; http://www.neurology.org/cgi/content/full/65/4/559

Obesity in older adults: Technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society.
Villareal DT, Apovian CM, Kushner RF, Klein S.
Obes Res 2005 Nov;13(11):1849-63.
Pubmed abstract
Free full-text: http://www.obesityresearch.org/cgi/reprint/13/11/1849


2003

Effects of volunteering on the well-being of older adults.
Morrow-Howell N, Hinterlong J, Rozario PA, Tang F.
J Gerontol B Psychol Sci Soc Sci. 2003 May;58(3):S137-45.
Pubmed abstract

Predictors of mortality in younger and older patients with heart failure and preserved or reduced left ventricular ejection fraction.
Kerzner R, Gage BF, Freedland KE, Rich MW.
Am Heart J 2003 Aug;146(2):286-90.
Pubmed abstract

Identifying factors associated with disability-related differences in breast cancer screening (United States).
Schootman M. Jeffe DB.
Cancer Causes and Control 2003;14(2):97-107.
Pubmed abstract
Full text: http://www.springerlink.com/content/q657207388464265/